Confirm Issue Button Doesn't Respond

Sometimes clicking Confirm Issue button doesn’t respond correctly. Typically, clicking Confirm Issue causes the Confirm issue box to be checked and crossed out but sometimes, more often than I’d like, it will ignore the click of the button. Refreshing the page will cause the box to reappear as checked and crossed off 100% of the time. I’ve tried different browsers and computers with the same results. Recently I decided to just move on with the rest of the ticket and eventually refresh the page towards the end and this works also.